-80℃ Cascade Cryogenic Refrigeration Circulator

Overview of Low-Temperature Refrigeration Circulators

Model: PLD-80/50

Temperature Control Range: -80℃ to RT (room temperature)

A low-temperature refrigeration circulator is a circulating device that precisely controls low-temperature environments, enabling cooling, constant-temperature maintenance, and circulating delivery of liquid media, thereby providing stable temperature support for various applications requiring low-temperature conditions.

To achieve an ultra-low temperature environment of -80°C, conventional refrigeration technologies can no longer meet the requirements; instead, a cascade refrigeration cycle system must be employed. Such equipment is known as a -80°C low-temperature refrigeration circulator and is widely used in fields such as biomedicine, chemical synthesis, and scientific research—areas that demand extremely precise temperature control.



The core principle of this type of equipment is the coordinated operation of two or more independent refrigeration cycles:

A single refrigerant cannot condense to -80℃ at ambient temperature; it must rely on the coordinated operation of a “high-temperature stage + low-temperature stage” dual-system configuration.

High-temperature refrigerant: commonly R404A or R22, responsible for initial heat dissipation;

Low-temperature refrigerant: Use R23 or R13 to achieve deep-cold output.

Recommended configuration: A two-stage cascade system (R404A+R23) is sufficient for -80℃ requirements, while a three-stage cascade system is suitable for ultra-low temperature applications below -120℃.



Key Features and Technical Advantages

Ultra-low Temperature Capability: Can stably maintain a working environment of -80°C, with some models reaching below -120°C.

Completely Closed-Loop Design: Prevents evaporation and contamination of the refrigerant, suitable for special heat-transfer fluids such as alcohol and silicone oil.

Multi-layered Safety Protection: Integrates multiple protective mechanisms including high-pressure, water‑cut-off, overload, and leakage protection, ensuring 24‑hour continuous operation.

Industrial‑Grade Durability: The compressor is from the American brand Copeland International, offering long service life and low noise levels.

High-precision temperature control: Utilizing a PID fuzzy controller and PLC system, temperature control accuracy can reach ±1℃, with some equipment even achieving ±0.05℃.

Temperature control accuracy: Directly affects the success or failure of experiments

Standard industrial grade: ±1℃, suitable for general cooling requirements;

High-precision, research-grade: ±0.05℃, equipped with a PID controller and a PT100 temperature sensor, ideal for precise reaction temperature control.

Recommendation: For applications sensitive to temperature fluctuations, such as enzymatic reactions, prioritize models with heating compensation, which achieve precise temperature control through cooling combined with minimal heating.



Typical Application Scenarios

Biological Sample Preservation: Used to store precious biological materials such as viruses, cells, DNA/RNA, ensuring long-term viability.

Low-Temperature Pharmaceutical Synthesis: Conducts high-purity drug synthesis at -80°C, suppressing side reactions and improving product yield.

Low-Temperature Treatment of Materials: In industrial processes such as metal cold treatment and cold assembly of bearings, it enhances material properties and assembly accuracy.

Laboratory auxiliary equipment: Used in conjunction with rotary evaporators, double-jacketed glass reactors, NMR spectrometers, and other instruments to provide a stable cold source.

-80℃～RT, Low-Temperature Refrigeration Circulator – Technical Specifications

Application Industries

1. Pharmaceutical: processes requiring temperature control, such as synthesis, hydrolysis, esterification, and etherification.

2. Chemical: distillation and purification, rubber grinding, cryogenic milling, and chemical synthesis.

3. Metal processing: cryogenic assembly, cryogenic quenching.

4. Food: Processing and storage of ultra-low-temperature foods such as tuna.

5. Semiconductor electronics: Environmental testing of components, simulated testing of electronic devices.

6. Aerospace: Heat sink experiments, environmental simulation tests for components, evaporative cooling environment simulation tests.

-80℃ Cascade Cryogenic Refrigeration Circulator

Cryogenic Refrigeration Cryocooler – Partial Component Detail Images

Control system display, branded compressor, condenser fan, plate heat exchanger, expansion valve, dryer filter, etc.

External Structural Diagram of the Cryocooler

Real-Product Photos